Managing liver dysfunction in parenteral nutrition
نویسندگان
چکیده
منابع مشابه
BAPEN Symposium 4 on ‘Managing complications in long-term parenteral nutrition’ Managing liver dysfunction in parenteral nutrition
Parenteral nutrition is life saving in patients with intestinal failure but liver dysfunction is commonly encountered, especially in neonates. Although abnormal liver function tests associated with short-term parenteral nutrition are usually benign and transient, liver dysfunction in both children and adults receiving long-term parenteral nutrition can progress to end-stage liver disease and li...
متن کاملTotal parenteral nutrition-induced liver dysfunction: evidence and pathogenesis
Results: Varied injuries to the liver are induced clinically and experimentally by progressive deterioration after a longer period of TPN infusion. The mechanisms of cholestasis and fibrosis in pathological changes include alteration of trace elements in hepatocytes, metabolic disturbance of fatty acid, calorie overload, lithocholate effect, sepsis, etc. The administration route of TPN is exclu...
متن کاملLiver Dysfunction Associated with Parenteral Nutrition: What Are the Options?
INTRODUCTION Patients who cannot support their nutritional needs via the enteral route due to intestinal failure often require parenteral nutrition (PN). Prolonged PN may be necessary in patients suffering from a variety of gastrointestinal motility, malabsorptive, or metabolic disorders (1). As the number of patients relying on prolonged PN support increases, associations between PN and an arr...
متن کاملParenteral Nutrition in Liver Resection
Albeit a very large number of experiments have assessed the impact of various substrates on liver regeneration after partial hepatectomy, a limited number of clinical studies have evaluated artificial nutrition in liver resection patients. This is a peculiar topic because many patients do not need artificial nutrition, while several patients need it because of malnutrition and/or prolonged inab...
متن کاملEffects of cyclic parenteral nutrition on parenteral-associated liver dysfunction parameters
INTRODUCTION One of the most common complications of parenteral nutrition (PN) is liver dysfunction (LD). Therapeutic approaches for LD include, among others, administering cyclic parenteral nutrition (cPN), allowing some hours for metabolic rest. The purpose of this study was to evaluate the effectiveness of cPN in treating PN-associated LD. MATERIALS AND METHODS A retrospective observationa...
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ژورنال
عنوان ژورنال: Proceedings of the Nutrition Society
سال: 2007
ISSN: 0029-6651,1475-2719
DOI: 10.1017/s002966510700585x